NATIONAL INSTITUTE FOR RESEARCH IN TRIBAL HEALTH

JABALPUR - 482003


(Established in 1984)

  NATIONAL INSTITUTE FOR         RESEARCH IN TRIBAL HEALTH

Publications

Phone: 0761 -2370800
Fax: 0761 -2672835
Email : rmrctjabalpur@rediffmail.com
Website :  http://www.nirth.res.in
Scope of Activities:

  • Situated in the city of Jabalpur in the state of Madhya Pradesh, the Regional Medical Research Centre for Tribals (RMRCT) conducts research on Haemoglobinopathies, Vector borne disease, other Communicable diseases and Nutritional disorders.
  • The studies in Haemoglobinopathies are confined to sickle cell anemia, G6PD Deficiency and α Thallasemia; the studies in vector borne diseases are restricted to the study of Malaria, Filaria and Dengue; the studies on other communicable diseases include Tuberculosis, Viral hepatitis, sexually transmitted infection including HIV/AIDS, Diarrheal diseases, etc.; the Nutritional studies include research on nutritional disorders and studies on fluorosis.

Thrust Areas:

The following are the thrust areas of RMRCT

  • Haemoglobinopathies and malaria.
  • Work on the genetic disorders by mapping the genetic traits/ diseases.
  • Work on bio-medical and behavioural aspects of malaria using technology driven laboratories developed by it over the years.
International Recognition:

  • RMRCT, Jabalpur is designated recently as WHO Collaborative Centre for Research on the Health of Indigenous People.
  • RMRCT, Jabalpur works in close coordination with many international organizations in collaborative research or organizing symposia, etc. e.g. Centre for Disease Control, London School of Tropical Medicine, Liverpool School of Tropical Medicine and Hygiene, UNICEF, WHO, DFID, USAID, US Embassy, etc.
Human Resource Development :

  • RMRCT, Jabalpur jointly with NIMR-Field Station, Jabalpur organises from time to time training workshop for medical officers on malariology.
  • RMRCT, Jabalpur also organizes various national/international symposia, workshops and trainings.
  • Students from various universities such as Rani Durgawati Vishwavidyalaya, Jabalpur, etc. have completed their M.Sc dissertation work under the guidance of scientists of the centre.
Recognition for Doctorate/Masters by a University:

  • Rani Durgawati Vishwavidyalaya, Jabalpur through a memorandum of understanding in 2008 has recognized the centre/ scientists for guiding bio-medical and socio-behavioural health research students for the degree of Ph.D.
  • The centre is also recognized for Ph.D work by Jiwaji University, Gwalior.

Major Achievements:

Significant achievements of RMRCT, Jabalpur are the following:

  • Tuberculosis laboratory of the Centre is recently recognized as Intermediate Referral
    Laboratory (IRL) beside State Referral Laboratory for HIV.
  • The Centre has established the H1N1p testing laboratory and is receiving samples from
    different parts of Madhya Pradesh.
  • Establishment of a
    • Sickle cell clinic at the NSCB Medical College, Jabalpur where regular diagnosis,
      counseling and treatment is given to the patients mostly from the rural areas.
    • Malaria clinic at the NSCB Medical College for prompt diagnosis.
    • Round the clock malaria clinic at Jagdalpur in Chhattisgarh (CG) to cater to the need of
      the rural tribal population.
  • On fluorosis, the nutritional supplementation and safe drinking water model of the centre
    has been accepted by the programme for prevention of the disease.
  • Important research projects undertaken on
    • Prevalence of pulmonary tuberculosis in tribal population of Madhya Pradesh

      The prevalence of pulmonary tuberculosis amongst Saharia primitive tribe was found to be 1,518
      per 100,000 against the national estimate of 299 in 2006. This requires urgent intervention.
    • Malaria in Baiga Chak of Dindori district

      The slide positivity rate was 27% with 87 % P. falciparum and 47% spleen rate which is highest in
      the state. The drug and insecticide policy is changed on the basis of our recommendations.
    • Comparative evaluation of commercially available rapid diagnostic tests (malaria Pf/Pv Kit)
      Vs. traditional and molecular techniques for malaria (Ongoing)

      Out of five commercially available RDTs, first response malaria antigen pLDH/HRP2 combo test
      was 95.8% sensitive and 58.8% specific for malaria. The bivalent kits are being introduced in the
      national programme on the basis of our recommendations.
    • Preparation of a field site for malaria vaccine trial in and around Jabalpur

      Anopheles culicifacies (Sporozoite rate = 0.42) and An. fluviatilis (Sporozoite rate = 0. 9) are
      playing an important role in the malaria transmission. The prevalence of P. falciparum and P.
      vivax
      was highest in 6-8 year and 4-6 year age group indicating that these age group needs to
      be vaccinated.
    • Genetic polymorphism analysis of merozoite surface protein-1(Msp1) gene of Plasmodium
      falciparum
      (Ongoing)

      The overall allelic prevalence was found higher in RO33 (40%) with 9 types of variants followed
      by K1 (36%) with 21 types of variants and MAD20 (24%) with 17 types of variants. No information
      is available on temporal variation and extent of polymorphism in MSP-1 gene from this region,
      which is the potential information for development of MSP-1 based multivalent malaria
      vaccine.
    • Prevalence of haemoglobinopathies in tribes of Madhya Pradesh (Ongoing)

      Sickle haemoglobin and G-6-PD deficiency are very common (range: 10% to 30% and 1% to
      9% respectively), reported for the first time, among the various tribes and scheduled caste
      population of tribe dominated Districts of Madhya Pradesh.
    • Fluorosis mitigation: Assessment, intervention and impact of intervention in fluorosis
      affected villages of Seoni district of Madhya Pradesh (Ongoing)
      About 12-15 % population is suffering from nonskeletal fluorosis and 3-4% population is suffering
      from skeletal fluorosis.
    • Fluorosis

      Skeletal deformities due to fluorosis are reversible in children by simple intervention i.e. safe
      drinking water and nutrition supplementation. This has been incorporated in the national
      programme for fluorosis prevention and control.
    • Health and nutritional profile of Baiga tribe of Balaghat district, Madhya Pradesh

      Acute respiratory infection (25%) and malaria (15%) are the major morbidities in Baigas of
      Balaghat district with high prevalence of malnutrition (<-3SD) 10.7% among pre-school children.
      This data has been generated for the first time in Baigas of Balaghat district.
    • Behaviour and vulnerability to reproductive morbidity among the tribal youths: A study
      among the Sahariyas of Gwalior district of Madhya Pradesh

      About 17% of the Sahariya youths of Gwalior district in the age group 15-24 years reported
      STI symptoms with poor knowledge and practice of various reproductive safeguards and safe
      sexual health behaviour.
    • Newborn care among tribes of Madhya Pradesh: A case study among the Bhils of Dhar
      district of Madhya Pradesh (Ongoing)

      Utilization of MCH services has considerably improved with antenatal care during the last
      pregnancy (89%), institutional deliveries (64%), and colostrums to newborn (59%) among the
      Bhils of Dhar district of Madhya Pradesh.
  • The Centre/scientists are recognized for PhD by Rani Durgawati Vishwavidyalaya, Jabalpur.
    Two PhD’s awarded.
  • Establishment of close linkages with the Tribal Welfare Department, Government of India
    as well as Government of Madhya Pradesh for providing technical assistance/evaluation of
    programmes and for receiving financial support for the research studies.

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