VECTOR CONTROL RESEARCH CENTRE

PUDUCHERRY - 605006


(Established in 1975)

  VECTOR CONTROL RESEARCH CENTRE

Publications

Phone: 0413 -2272396
Fax: 0413 -2272041
Email : vcrc@vsnl.com
Website :  http://www.vcrc.res.in
Scope of Activities:

Situated at Puducherry, the Vector Control Research Centre (VCRC) is engaged on research on vector borne diseases such as Malaria, Filariasis, Dengue, Chikungunya, Japanese encephalitis (JE) and Leishmaniasis.

Thrust Areas:

The following are the thrust areas of VCRC

  • Development of better strategies for vector borne disease control/elimination.
  • Development of vector management strategies.
  • Surveillance tools for monitoring vector resistance to insecticides.
  • Development of newer tools/products for vector identification, surveillance and control.
  • Epidemiological studies for optimizing of intervention strategies.
  • Technical support to the national and state programmes.
  • Epidemic/epidemiological investigations.
  • HRD activities towards capacity building.
International Recognition:

VCRC is a declared WHO Collaborating Centre for Research & Training in Lymphatic Filariasis and Integrated Methods of Vector Control.
Human Resource Development :

  • The Ph. D. and P.G. programmes of the Centre are recognised by the Pondicherry University,
    Puducherry.
  • The Centresí broad areas of research for Ph.D programme are zoology, epidemiology, microbiology
    and chemistry.
  • The Centre also runs the PG diploma course in medical entomology
  • Short term informal training courses in epidemiology & control of vector borne diseases are
    organized by the Centre
Recognition for Doctorate/Masters by a University:

Centre is recognized by the University of Madras for the PhD Degree. Several staff members serve as Guides/supervisors and members of the Doctoral Committees of the University.

Major Achievements:

Significant achievements of VCRC are the following

  • Established a museum and developed DNA barcodes for several species of mosquitoes
    (vectors) from different regions of the country.
  • Developed a production technology for a biolarvicide, Bacillus thuringiensis var. israelensis
    and transferred to 8 companies.
  • Identified two mosquito pupicides, from Pseudomonas fluorescens and Bacillus subtilis var.
    subtilis and processes for their production optimized.
  • Developed production technologies for cyclosporin A - an immunosuppressive agent,
    thrombinase - a blood clot dissolving enzyme and an enzyme useful in leather industry for
    dehairing of animal skins.
  • Developed a laboratory scale process for a synthetic insect repellent (DEPA) and a controlled
    release formulation of an insect growth regulator (DPE-28) for mosquito larval control.
  • Identified two anti-filarial lead molecules, from indigenous medicinal plants viz., 5-hydroxy-
    2-methyl-1, 4-naphthalenedione, from Plumbago rosea and a monoterepene with phenolic
    properties from Trachyspermum ammi. Developed a PCR assay (rDNA-ITS2 region based) for
    identification of sibling species of Anopheles fluviatilis one of the major vectors of malaria.
    Developed a RT-PCR assay to detect infective larvae of filarial parasites in vectors.
  • Identified molecules up-regulated/produced in the vector mosquito, Culex quinquefasciatus,
    during the development of Wuchereria bancrofti.
  • Studied genetic polymorphism of Wuchereria bancrofti from different geographical regions
    of the country and identified 4 parasite/endosymbiont molecules (gp15/400, ftsZ, iPGM,
    HtrA) as potential targets for antifilarial drug development.
  • Developed malaria control strategies for coastal (Pondicherry and Rameswaram Island),
    riverine (Sathanur), and urban (Salem) areas in Tamil Nadu, and tribal areas in Koraput,
    Orissa.
  • Master plans for mosquito control developed for township, Neyveli Lignite Corporation, Tamil
    Nadu, Muncipal Corporation, Kochi (Kerala), Muncipal Corporation, Bangalore (Karnataka)
    and Muncipal Corporation, Vishakhapatnam (Andhra Pradesh).
  • Integrated vector control strategies developed for bancroftian filariasis in Puducherry and
    brugian filariasis in Shertallai, Kerala.
  • Developed a community based strategy for early treatment of malaria cases involving local
    traditional health providers (Dishari).
  • Developed strategy for the control of Aedes albopictus in rubber plantations in Kerala
    Prepared a lymphatic filariasis transmission risk map for the entire country, using the Geo-
    Environmental Risk Model (GERM).
  • Developed a DEC-fortified salt strategy as a supplement to mass drug administration for
    accelerating elimination of lymphatic filariasis.
  • Prepared guidelines on programme implementation for programme managers and drug
    distributors towards capacity building for the elimination of lymphatic filariasis.
  • Organised regional training course on comprehensive vector control for vector borne
    disease control programme managers.

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